What Are Peptides
Essentially, a short chain of
amino acids fused together by a bond is referred to as a peptide. This chain
typically comprises 50 amino acids or less with amino carboxyl end. Peptides
can be manufactured, derived from food consumed, and also
exist naturally in the body.
These short chains of amino acids
can be found in all cells of the human body. They are useful for effective
stimulation of hormones, including the protein-based growth hormone (GH).
Peptides are of different types, including polymers, oligopeptides and
neuropeptides.
Since peptides and proteins both
comprise amino acids, they are often confused with or thought to be the same.
However, this is not very accurate as the two differ in terms of their precise
composition. Peptides are described as having a maximum of 50 amino acids,
while proteins have more.
Types of USA peptides
A wide range of USA
Peptides are obtainable, with new ones added from time to time. Some of
these are more suited to specific purposes like muscle mass building, fat
burning or performance enhancement.
The variety of peptide offerings
on the market are categorized into groups, based on their mode of action. Some
of the most popular groups and peptides that fall under them are as follows.
Growth Hormone
Releasing Hormones (GHRH)
As the name implies, GHRH helps
to stimulate secretion of growth hormone. The specific type of peptide used
determines theextent of secretion induced. It is important to note that these
substances have a limit to their effectiveness. Surpassing the saturation dose,
which may vary between individuals, will not improve the amount of human growth
hormone (HGH) that is secreted. Below are some peptides that fall in the GHRH
group.
·
CJC 1295 No DAC / MOD-GRF (1-29)
Modified GRF
(1-29) is also known asCJC 1295 No DAC orCJC1295 without DAC. It is helpful in
stimulating muscle growth and fat burning, as well as slowing aging. It is
thought to also help its consumers sleep better. The half-life time of MOD-GRF
(1-29) is about a half hour.
·
CJC 1295 DAC
In some way,
it is the opposite of Modified GRF (1-29) yet serving a similar purpose.
CJC-1295 with DAC mainly differs from the other peptides in terms of the duration
of its effects. The half-life is estimated at about a week, making it ideal to
checkmate frequent use.
·
HGH Fragment 176-191
As the name
implies, this peptide is a fragment of human growth hormone. It is more
specifically a modified form of the amino acids 176-191 in the C-terminal section
of the latter substance. It is mostly used by bodybuilders to enhance fat
burning for improved and more obvious muscle growth. For weight loss, HGH
Fragment 176-191 is thought to be considerably more effective than regular
growth hormone. Also as a result of positive effects on IGF-1 levels, it offers
anti-aging benefits.
·
Sermorelin
Having a
similar structure to CJC-1295, Sermorelin is commonly used for anti-aging
purposes. However, it is also considered useful for muscle building. It
accounts for 29 amino acids of the 44 that make up growth hormone releasing
hormones. Studies have shown that this peptide is very potent for improving HGH
levels. It was observed that the 1-29 amino acid chain is mainly responsible
for the ability of GHRH to stimulate release of growth hormone by the
pituitary. However, its half-life is very short about 10 minutes or less.
Growth Hormone
Releasing Peptides (GHRP)
These compounds may be considered
an improvement on GHRH in terms of ability to induce growth hormone secretion.
GHRP is thought to cause secretion of larger amounts of GH in the body. Unlike
in the case of GHRH, you do not need to aim at specific times to take advantage
of pulse produced by your body. Growth hormone releasing peptides produce
growth hormone spurts practically whenever they are consumed. They are also
available in different types, including the following:
·
GHRP-6
GHRP 6 is a
very potent peptide for promoting growth hormone release used for muscle
building, weight loss and anti-aging purposes, as well as fighting inflammation
and boosting recovery. Some professional bodybuilders are believed to use it
together with steroids for greater potency. The peptide not only stimulates the
pituitary to produce growth hormone, but also suppresses release impedance from
somatostatin.
·
GHRP-2
Though
slightly stronger than GHRP-6, which is powerful for growth hormone release,
GHRP2 is used for quite similar purposes. But it does not improve appetite unlike
the other peptide. This may make it more ideal for improving lean muscle mass.
Furthermore, it does not desensitize when taken in low doses without observing
breaks as is required for other peptides.
·
Ipamorelin
Ipamorelin is
a peptide with the potential to stimulate GH release without resulting in
issues associated with others. Just like GHRP-6, it stimulates the pituitary and
suppresses somatostatin. Not the most powerful growth hormone releasing
peptide, but it neither causes a drastic surge in appetite nor higher prolactin
or cortisol levels, making them a favorite for some consumers.
·
Hexarelin
Users get even
greater growth hormone release from this peptide than both GHRP-6 and GHRP-2.
Much like other GHRP and GHRH peptides, it is believed to be useful for muscle
building, fat loss and anti-aging. Hexarelin is stronger than practically all
other growth hormone releasing peptides at all dosing levels, meaning it has
higher potential to desensitize, regardless of dose or whether breaks are
observed.
Insulin-like Growth Factor-1
(IGF-1)
Also known as Somatomedic C, IGF-1
has become one of the more popular peptides used for muscle building over the
last ten years. This class of peptides is used by bodybuilders to improve the
insulin-like growth of muscles, great for targeting specific muscle groups. A
prominent user is thought to have been Englishman Dorian Yates, who was named
Mr. Olympian for six straight years in the 1990s. This contributed to make many
professional bodybuilders to include it in their regimen as well. IGF-1 also
exists in different variations.
·
IGF-1 LR3
Comprising 83
amino acids, IGF 1 LR3 is the most popular variant of IGF-1 available on the
market today, with an extra 13 amino acids to the sequence of the standard
insulin-like growth factor-1. It helps with fat burning, quicker recovery and
slowing aging in addition to bodybuilding. The polypeptide vaunts qualities
that make it much more powerful than normal IGF-1. It boasts a longer half-life
of up to 30 hours, compared to the IGF-1’s 15 hours.
·
PEG MGF - Mechano Growth Factor (with PEG)
Also known as
PEG-MGF, this peptide not only helps to promote muscle growth, but also to
cause new muscle cells to be formed. The IGF-1 form is linked to polyethylene
glycol (PEG), which differentiates it from ordinary mechano growth factor. Consequently,
the half-life of MGF increases from minutes to days. It is more ideal to use
PEG-MGF after workouts due to the mechano-sensitive nature of MGF. The peptide
facilitates faster recovery from muscle damage, being that it is activated by
mechanical stimulus.
The list of peptides mentioned so
far is of course not exhaustive. There are numerous other types on the market,
some of which may not be necessarily beneficial for bodybuilding.
Are peptides legal to use?
The legality of peptides is
determined by the reason for which they are used. Peptides for sale online are
only for research purposes, which means you can only buy peptides for research
purposes and never for human consumption.
Adequate testing is required for
any substance to be approved for human use, and for these substances the
sufficient research needed to ascertain their safety is not yet available. This
is a major reason why it is considered illegal to use peptides for
bodybuilding.
Each type of peptide has specific
purposes for which it is more useful including growing bigger muscles, burning
of body fat, improve muscle recovery and slow aging. These compounds are in
many cases beneficial because of how they boost release of growth hormone by
the pituitary gland. GH secretion is amplified when GHRH and GHRP substances
are used together. However, always remember that only research purposes makes
the use of peptides legal.
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